Portable Oxygen Concentrators with Continuous Flow (2025)

While there are many portable oxygen concentrators on the market with pulse flows, some patients don’t know that there are also devices that incorporate constant or continuous flow settings. These are very useful during sleeping hours, and they also provide portable oxygen for those with more serious oxygen needs, like those patients with chronic obstructive pulmonary disease (COPD).

At Main Clinic Supply, we have multiple portable oxygen concentrators with continuous oxygen flows. These are useful for patients who want to stay active, and our continuous flow portable oxygen concentrators are all FAA-approved for use in airplanes. Here’s a quick rundown of the devices we have on offer here at Main Clinic Supply.

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Portable Oxygen Concentrators with Continuous Flow (1)

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  • OxLife Liberty2 - True Continuous Flow - Portable Oxygen Concentrator

    Portable Oxygen Concentrators with Continuous Flow (2)

    OxLife Liberty2 - True Continuous Flow - Portable Oxygen Concentrator

    • Constant Flow .5-2 LPM
    • Pulse FlowSettings 1-10
    • Only 7.8 Pounds
    • FAA Approved

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    Portable Oxygen Concentrators with Continuous Flow (3)

  • O2 Concepts OxLife Independence - Portable Oxygen Concentrator

    Portable Oxygen Concentrators with Continuous Flow (4)

    O2 Concepts OxLife Independence - Portable Oxygen Concentrator

    • Constant Flow 1 - 3 LPM
    • Pulse Flow 1 -6
    • FAA Approved
    • Built-in Mobile Cart

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    Portable Oxygen Concentrators with Continuous Flow (5)

  • GCE Zen-O Portable Oxygen Concentrator

    Portable Oxygen Concentrators with Continuous Flow (6)

    GCE Zen-O Portable Oxygen Concentrator

    • Constant Flow up to 2 LPM and Pulse Dose 1-6
    • Long Battery Life
    • FAA Airline Approved
    • Carry Bag and Case Included
    • CPAP compatible

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  • CAIRE SeQual Eclipse 5 - Portable Oxygen Concentrator

    Portable Oxygen Concentrators with Continuous Flow (7)

    CAIRE SeQual Eclipse 5 - Portable Oxygen Concentrator

    • Constant Flow up to 3 LPM, Pulse Dose Settings 1 to 9
    • AutoSAT Technology
    • FAA Airline Approved
    • Extended Battery Life
    • CPAP Compatible

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  • Portable Oxygen Concentrators with Continuous Flow (8)
  • Portable Oxygen Concentrators with Continuous Flow (9)
  • Portable Oxygen Concentrators with Continuous Flow (10)
  • Portable Oxygen Concentrators with Continuous Flow (11)

How Continuous Flow Works

Continuous flow in a portable oxygen concentrator (POC) refers to a mode of oxygen delivery where the device emits a steady stream of oxygen, regardless of the user’s rate of breathing. This is particularly beneficial for individuals who require a constant supply of oxygen to maintain optimal saturation levels.

In continuous flow mode, the concentrator draws in ambient air, filters out nitrogen, and compresses the purified oxygen. This oxygen is delivered through a nasal cannula at a consistent rate measured in liters per minute (LPM). The flow rate is adjustable to match the user’s prescribed oxygen requirements.

Continuous flow is often recommended for individuals who use oxygen while sleeping, those with lower breath rates, or those with higher oxygen demands. It also supports compatibility with oxygen delivery accessories, such as CPAP or BiPAP machines.

Due to the constant oxygen output, POCs operating in continuous flow mode generally consume more power and offer shorter battery life compared to pulse models. However, their reliability and suitability for various medical conditions make them a preferred choice for many.

What to Consider in a Continuous Flow Unit

Factor Why It’s Important
Additional Flow Settings
  • • Extends the life of the device when the patient doesn’t require constant oxygen flow.
  • • The device will only provide oxygen when the patient needs it.
  • • The device will be able to adapt to different levels of activity.
If it’s Approved for Air Travel
  • • The FAA doesn’t approve every portable oxygen concentrator for the safety of the patient and fellow passengers.
  • • Unshielded portable oxygen concentrators can interfere with airplane instrumentation.
  • • When in cabins over altitudes of 8,000 feet, unapproved portable oxygen concentrators may not deliver sufficient oxygen.
  • • Patients won’t have to procure medical-grade oxygen from an aircraft operator, which can be costly and difficult to coordinate.
Battery Life Expectancy
  • • Longer battery durations mean more activity.
  • • Patients won’t have to be plugged into AC or DC (12V) power sources for oxygen.

Important note: Continuous flow portable oxygen concentrators tend to drain battery life faster, thanks to the constant outflow of oxygen. Some models allow for a user to “hot swap” batteries, which will extend battery life expectancy by switching in new batteries when the previous one no longer has power.

Charging/Plug-In Method
  • • Provides the ability to plug into a wall outlet to save and charge the battery.
  • • Some models allow for remote charging when using a DC (12V) power source – these chargers are typically found in cars through the cigarette lighter.
  • • External battery chargers allow you to charge batteries independently while continuing to charge the device.
Sound Levels

Having lower sound levels will make the device more convenient when:

  • • Sleeping
  • • In quiet environments
  • • Watching television
Carrying Methodology
  • • Portable oxygen concentrators can be heavy, especially those with continuous oxygen settings, since these need larger compressors and motors.
  • • Having features, like wheels, shoulder straps, and carrying cases, adds convenience, even when a device is relatively lightweight.

Why Continuous Flow is Useful in a Portable Oxygen Concentrator

When evaluating portable oxygen concentrator options, two primary delivery methods are typically available: continuous flow and pulse dose. Continuous flow systems provide a steady stream of oxygen regardless of the user's inhalation, delivering oxygen consistently at an adjustable rate, as indicated by the name.

Pulse flow delivery faces a problem when a patient sleeps, as this type of flow setting relies on a patient’s breathing; the slower and shallower breaths that happen at night can cause the portable concentrator to not trigger. The continuous and steady stream of oxygen generated by a portable concentrator with constant flows ensures that the patient receives an adequate level of oxygen they need for rest.

Compatibility with CPAP/BiPAP machines

Continuous flow portable oxygen concentrators are the only portable oxygen concentrators that are compatible with CPAP/BiPAP machines. This benefits patients with sleep apnea who can use a mask with an oxygen port for connectivity with their portable concentrator.

When the Patient Has Higher Oxygen Needs

Certain conditions, like COPD, require higher levels of oxygen that aren’t practical with a machine providing only pulse dose flows. As a general rule, continuous oxygen concentrators designed for portability have higher LPM capabilities.

When the Patient Is Exerting Themselves

Strenuous physical activity increases the oxygen needs of portable oxygen concentrator users. While some machines have pulse flows that accommodate physical activity, the irregular breathing patterns that come with exercise can make pulse flows less reliable. The steady stream of oxygen from a continuous unit will ensure that those engaging in rigorous activity will have the steady stream of oxygen they need.

If a Patient Is in Respiratory Distress

The constant flow of oxygen that a portable oxygen concentrator of this type provides for patients experiencing emergency respiratory situations is very beneficial. This flow of oxygen can stabilize a patient and potentially prevent hypoxia.

Quick Reference Guide

Choosing the right portable oxygen concentrator with continuous flow settings can be a daunting task, but we’re here to make it simple. Our quick reference guide outlines the primary advantages of each model, providing a clear comparison to assist in identifying the option that best aligns with individual lifestyle needs and oxygen therapy requirements.

Highest Quality:
CAIRE SeQual Eclipse 5

With a continuous flow rating of 3 LPM and pulse flows ranging from 1 to 9, the CAIRE SeQual Eclipse 5 is a fully-featured portable oxygen concentrator. It’s accepted for airline use by the FAA, and it also has CPAP compatibility.

Its autoSAT technology also changes pulse settings as the patient’s breathing changes to ensure the prescribed amount of oxygen is always administered.

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Best Budget:
GCE Zen-O Portable

While the GCE Zen-O Portable is on the heavier side at 10 pounds, it’s definitely one of the more budget-friendly continuous flow oxygen concentrators available.

It provides six pulse dose settings in addition to its 2 LPM continuous flows. It is also CPAP compatible and includes a carry bag and case.

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Lightweight:
Oxlife Liberty2

While continuous flow settings add weight to a unit, the Oxlife Liberty2 keeps its weight down to about seven pounds. It also has its own carrying bag, which increases its portability.

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Main Clinic Supply Testimonials

“This has been the best online buying experience I have ever done, unlike other places when I was shopping and reading reviews Main Clinic Supply answered the phone right away every time, my package said overnight before 10:30 AM, it was here 10:15 AM the next day! Can’t say enough good thing, they realize you need your oxygen now they get it to you fast!”

— John, WA

“I was in need of purchasing a portable oxygen concentrator. The specialist I chatted with was Leo Castro. He was amazing.

He answered all my questions, made suggestions and never once did I feel any pressure to make a purchase.

He expedited the shipment and kept track of where it was so he could let me know. Then followed up to make sure everything I ordered had arrived safely and if I had any questions.

I am SO GLAD I chose Main Clinic Supply and for Leo. Thank you, MCS!!!”

— Molly M.

“Just received my new Inogen Rove 6 and could not be happier! The ordering process was made so simple and easy and the customer service from my specialist Ben Sletta was amazing. This was my second purchase through Main Clinic Supply and I can confidently say that they are exceptional and have a very happy customer for life! Thank you :)”

— Laurie L.

Speak To One Of Our Oxygen Specialists!

Not sure which oxygen concentrator or setup is best for you? Our expert Oxygen Specialists are here to help!

1-800-775-0942

Portable Oxygen Concentrators with Continuous Flow (13)

“This has been the best online buying experience I have ever done, unlike other places when I was shopping and reading reviews Main Clinic Supply answered the phone right away every time, my package said overnight before 10:30 AM, it was here 10.15 AM the next day! Can’t say enough good thing, they realize you need your oxygen now they get it to you fast!”

- John, WA

Get our Ultimate Freedom Package!

Save big with our freedom package and get the Inogen One Rove 6—the latest in portable oxygen technology—along with the Inogen At-Home Oxygen Concentrator, plus a free travel case.

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Portable Oxygen Concentrators with Continuous Flow (14)

Portable Oxygen Concentrators with Continuous Flow (15)

Portable Oxygen Concentrators with Continuous Flow (16)

Portable Oxygen Concentrators with Continuous Flow (17)

Portable Oxygen Concentrators with Continuous Flow (18)

Portable Oxygen Concentrators with Continuous Flow (19)

Portable Oxygen Concentrators with Continuous Flow (20)

Portable Oxygen Concentrators with Continuous Flow (21)

Portable Oxygen Concentrators with Continuous Flow (22)

Portable Oxygen Concentrators with Continuous Flow (23)

Inogen® Rove 6 Portable Oxygen Concentrator and Inogen At Home® Stationary Oxygen Concentrator Bundle

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Portable Oxygen Concentrators with Continuous Flow (2025)

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